TSUKUBA, Japan, Jan 18, 2022 - (ACN Newswire) - Tiny dressings that generate electricity in response to movement could accelerate wound healing and tissue regeneration. Scientists in Taiwan reviewed the latest advances and potential applications of wound healing technology in the journal Science and Technology of Advanced Materials.
The natural wound healing process involves complex interactions between ions, cells, blood vessels, genes and the immune system; with every player triggered by a sequence of molecular events. An integral part of this process involves the generation of a weak electric field by the damaged epithelium - the layer of cells covering tissue. The electric field forms as a result of an ion gradient in the wound bed, which plays an important role in directing cell migration and promoting blood vessel formation in the area.

Scientists discovered in the mid- to late-1900s that stimulating tissue with an electric field could improve wound healing. Current research in this field is now focused on developing small, wearable, and inexpensive patches that aren't encumbered by external electrical equipment.

This has led to research on piezoelectric materials, including natural materials like crystals, silk, wood, bone, hair and rubber, and synthetic materials such as quartz analogs, ceramics and polymers. These materials generate an electric current when exposed to mechanical stress. Nanogenerators developed using the synthetic materials are especially promising.

For example, some research teams are exploring the use of self-powered piezoelectric nanogenerators made with zinc oxide nanorods on a polydimethylsiloxane matrix for accelerating wound healing. Zinc oxide has the advantage of being piezoelectric and biocompatible. Other scientists are using scaffolds made from polyurethane and polyvinylidene fluoride (PVDF) due to their high piezoelectricity, chemical stability, ease of manufacturing and biocompatibility. These and other piezoelectric nanogenerators have shown promising results in laboratory and animal studies.

Another type of device, called a triboelectric nanogenerator (TENG), produces an electric current when two interfacing materials come into and out of contact with each other. Scientists have experimented with TENGs that generate electricity from breathing movements, for example, to accelerate wound healing in rats. They have also loaded TENG patches with antibiotics to facilitate wound healing by also treating localized infection.

"Piezoelectric and triboelectric nanogenerators are excellent candidates for self-assisted wound healing due to their light weight, flexibility, elasticity and biocompatibility," says bioengineer Zong-Hong Lin of the National Tsing Hua University in Taiwan. "But there are still several bottlenecks to their clinical application."

For example, they still need to be customized so they are fit-for-size, as wound dimensions vary widely. They also need to be firmly attached without being negatively affected or corroded by the fluids that naturally exude from wounds.

"Our future aim is to develop cost-effective and highly efficient wound dressing systems for practical clinical applications," says Lin.

Further information
Zong-Hong Lin
National Tsing Hua University
Email: [email protected]

Research paper: https://www.tandfonline.com/doi/full/10.1080/14686996.2021.2015249

About Science and Technology of Advanced Materials (STAM)

Open access journal STAM publishes outstanding research articles across all aspects of materials science, including functional and structural materials, theoretical analyses, and properties of materials. https://www.tandfonline.com/STAM

Dr. Yoshikazu Shinohara
STAM Publishing Director
Email: [email protected]

Press release distributed by Asia Research News for Science and Technology of Advanced Materials.

Copyright 2022 ACN Newswire. All rights reserved. www.acnnewswire.comTiny dressings that generate electricity in response to movement could accelerate wound healing and tissue regeneration. Scientists in Taiwan reviewed the latest advances and potential applications of wound healing technology in the journal Science and Technology of Advanced Materials.

The crypto market cap is down by roughly $100 billion in a day as bitcoin and most altcoins went on another ride south.

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Toyota City, Japan, Jan 18, 2022 - (JCN Newswire) - At Toyota, we have made repeated adjustments to our production plans due to a parts shortage resulting from the spread of COVID-19, causing various inconveniences to our customers and all parties concerned. We would like to express our gratitude to everyone involved for their immense support in helping us maintain production.
Our global production plan in February 2022 is expected to be around 700,000 units. Current demand is very strong, therefore we were aiming for a high February production plan. However, due to the impact of the continuing demand for semiconductors across all industries, we have adjusted our production plan by around 150,000 units globally.

As a result of the revision, the full-year production forecast for the fiscal year ending March 31, 2022 is expected to be lower than the previous forecast of 9 million units.

With regards to the shortage of semiconductor-related parts, we will continue to examine the situation and consult with all companies involved in considering the use of substitutes where possible in anticipation of a continuing shortage.

We will also continue to work with our suppliers in strengthening the supply chain and make every effort to deliver vehicles to our customers as soon as possible.

The following is the schedule for the suspension of domestic operations in February due to the plan revisions. We would like to offer our sincerest apologies to our customers and suppliers for the various inconveniences these adjustments may cause.


Copyright 2022 JCN Newswire. All rights reserved. www.jcnnewswire.comAt Toyota, we have made repeated adjustments to our production plans due to a parts shortage resulting from the spread of COVID-19, causing various inconveniences to our customers and all parties concerned.

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