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HONG KONG, Feb 7, 2022 - (ACN Newswire) - SinoMab BioScience Limited ("SinoMab" or the "Company", together with its subsidiaries, the "Group", stock code: 3681.HK), a Hong Kong-based biopharmaceutical company dedicated to the research, development, manufacturing and commercialization of therapeutics for the treatment of immunological diseases, is pleased to announce that, on 21 January 2022, an Investigational New Drug application ("IND", for multiple sclerosis) for SN1011 has been filed with and accepted, on 28 January 2022, by the Center for Drug Evaluation (the "CDE") of the National Medical Products Administration of China (the "NMPA"). The Company plans to initiate the Phase II clinical study in China upon approval of the present IND. The present IND submission, once granted, will enable the Company to conduct comprehensive clinical development program in China which leads to indication for treatment of multiple sclerosis.

SN1011 is the Company's third generation, covalent reversible BTK inhibitor designed for higher selectivity, superior efficacy and improved safety for the long-term treatment of systemic lupus erythematous, pemphigus vulgaris, multiple sclerosis, rheumatoid arthritis, and other immunological diseases. SN1011 differentiates from existing BTK inhibitors currently available in the market, such as Ibrutinib, in terms of mechanism of action, affinity, selectivity and safety.

Dr. Shui On LEUNG, Chairman, Executive Director and Chief Executive Officer of SinoMab said that: "after the Company announced earlier the Completion of Enrollment in Phase III Clinical Trial in China for its Flagship Product, SM03, an IND application (for multiple sclerosis) for SN1011 has been filed with and accepted by the Center for the CDE of the NMPA, which will accelerate the progression of the Phase II clinical study and clinical development program related to indication for treatment of multiple sclerosis, fully reflecting the Company's efficient implementation of new drug R&D programs. We are absolutely confident in the enormous prospects of SN1011's clinical development. In the future, the Company will accelerate the program to further expand its product pipeline and strive to bring benefits to patients."

About SinoMab BioScience Limited
SinoMab BioScience Limited (stock code: 3681.HK) is dedicated to the research, development, manufacturing and commercialization of therapeutics for the treatment of immunological diseases. The Company's flagship product SM03 is a potential global first-in-target mAb against CD22 for the treatment of rheumatoid arthritis (RA) and is currently in Phase III clinical trial for rheumatoid arthritis in China, which has been recognized as one of the significant special projects of Significant New Drugs Development of the Twelfth Five-Year Plan Period and the Thirteenth Five-Year Plan Period. In addition, the Company possesses other potential first-in-target and first-in-class drug candidates, some of which are already in clinical stage, with their indications covering rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), pemphigus vulgaris (PV), non-Hodgkin's lymphoma (NHL), asthma, and other diseases with major unmet clinical needs.



Copyright 2022 ACN Newswire. All rights reserved. www.acnnewswire.comSinoMab BioScience Limited ("SinoMab" or the "Company", together with its subsidiaries, the "Group", stock code: 3681.HK), a Hong Kong-based biopharmaceutical company dedicated to the research, development, manufacturing and commercialization of therapeutics for the treatment of immunological diseases, is pleased to announce that, on 21 January 2022,

Toyota City, Japan, Feb 7, 2022 - (JCN Newswire) - Fukuoka City and Toyota Motor Corporation (Toyota) have signed a partnership agreement aiming for the early realization of a hydrogen society. They will work closely with Commercial Partnership Technologies Corporation (CJPT), which works on commercial projects, to promote a wide range of collaborative initiatives to achieve the goal. As a first step, they have commenced discussions regarding the introduction of fuel cell vehicles.

Fukuoka City has focused on the potential of hydrogen energy from an early stage and initiated the Hydrogen Leader City Project. As part of the project, the city launched the world's first initiative to produce hydrogen from public household sewage and supply it to fuel cell vehicles. It was also the first city in Japan to undertake various verification tests for trucks and motorcycles equipped with fuel cell technologies.

Toyota views hydrogen as a promising energy form to achieve carbon neutrality. In order to become a hydrogen society, it has sought to broaden customer choice through sales of its Mirai fuel cell vehicle, development of hydrogen-engine vehicles, and promotion of commercial vehicles in collaboration with CJPT, etc. The company has also promoted wide-ranging partnerships that extend beyond the automotive industry.

Fukuoka City and Toyota have held numerous talks with regard to making hydrogen more familiar to residents, and encouraging its sustainable and practical use. In fact, their first collaboration in the field of hydrogen was implemented in November 2021 during the final round of the Super Taikyu Series. In this race, Toyota used hydrogen produced from the city's public household sewage to power its hydrogen-engine vehicles.

Under the terms of the partnership agreement, Fukuoka City and Toyota in cooperation with CJPT will discuss a range of other hydrogen-related topics as follows: developing and using vehicles that can support social infrastructure and creating logistics models for them, using hydrogen energy at resident-centered facilities and events, and revising the regulations required for realizing a hydrogen society. To begin with, discussions are being held on the use of fuel cell vehicles for school meal delivery trucks and the city's garbage trucks, as well as deploying Moving e mobile power generation and supply systems.

Going forward, Fukuoka City, Toyota and CJPT will work together to develop and verify technologies related to producing, transporting, and using hydrogen. By helping to expedite the implementation of these technologies, the aim is to build a society in which hydrogen plays a major role. They also plan to actively engage in initiatives that contribute to the realization of carbon neutrality both in Japan and around the world.


Copyright 2022 JCN Newswire. All rights reserved. www.jcnnewswire.comFukuoka City and Toyota Motor Corporation (Toyota) have signed a partnership agreement aiming for the early realization of a hydrogen society.

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HONG KONG, Feb 7, 2022 - (ACN Newswire) - Synergy Group Holdings International Limited, stock code 1539.HK ("Synergy Group" or "The Group")(1) has successfully acquired verification statements of Greenhouse Gas (GHG) emissions granted by CMA Testing and Certification Laboratories under CMA Industrial Development Foundation Limited (CMA Testing(2)). The Group's projects were quantified to achieve emission by a total of 7,146.74 tonnes of CO2e (Carbon Dioxide Equivalent)(3). The GHG emission inventories have been verified in accordance with ISO14064-3:2019(4) as meeting the requirement of ISO14064-1:2018(4).

The Group Chairman and Chief Executive Officer Mr. Mansfield Wong commented, "It is a global uphill battle when it comes to reaching carbon neutral targets. Our goal is to reduce GHG emissions and strive to achieve carbon neutrality in the near future. The Group is actively formulating a commercial scheme to assist other companies in neutralizing their GHG emissions."

As of today, the Group has verified 7,146.74 tonnes of CO2e in total, which is estimated to be accounted for approximately 1% of the Group's total GHG emission inventory, the remaining inventories are being certified. Current carbon credit prices(5) are quoted by different international Carbon Credit Exchanges(5) ranging from RMB56 to EUR89 per tonne. The Group expects the global carbon credit prices(5)and market-based emission trading schemes continued to grow gradually as we are approaching the targets of Hong Kong's Climate Action Plan 2050(6), China's Carbon Dioxide Peaking 2030(7) and Carbon Neutrality 2060(7). Driving GHG emission is imminent action to curb global warming effects, the Group has set out its priorities for investing in carbon markets. The Group is committed to creating environmental sustainability through its experienced GHG emission management and green technological innovations.

Media enquiries:

New Smile Limited Strategic IR & PR Consultancy
Tel: +852 2126 7076
Jenny Lai [email protected]
Jenny Cheung [email protected]

Notes to editors:

1. Synergy Group Holdings International Limited ("Synergy Group" or "The Group")

Founded in 2008, Synergy Group Holdings International Limited (Stock code: 1539.HK), as the first Energy Service Company (ESCO) to be listed on the Hong Kong Stock Exchange, is one of the leading integrated energy saving and management solutions providers based in Hong Kong. The Group together with its subsidiaries, is principally engaged in design and customisation, investment, installation and commissioning, operation and maintenance of (i) energy efficiency technology; (ii) renewable energy; and (iii) energy storage and distributed energy resources. Serving clients in over 20 countries, businesses cover large multi-million projects in Malaysia, Indonesia and South Africa.

2. CMA Testing

Established since 1979, CMA Testing, a subsidiary of The Chinese Manufacturers' Association of Hong Kong, is a large-scale quality assurance center, specializes in testing, inspection and certification services. CMA Testing is also a third-party laboratory accredited by The Hong Kong Laboratory Accreditation Scheme (HOKLAS) and an inspection body accredited by The Hong Kong Inspection Agency Accreditation Scheme (HKIAS). CMA Testing's global footprint spans over 12 countries in Asia, Middle East, Europe and North America.

3. Carbon Dioxide Equivalent (CO2e)

CO2 refers to Carbon Dioxide, while CO2e stands for "Carbon Dioxide Equivalent" which includes CO2 and other greenhouse gases. For any quantity and type of greenhouse gas, CO2e signifies the amount of CO2 which would have the equivalent global warming impact.

4. ISO14064 Greenhouse Gas Calculation and Verification Management System

ISO14064-1: Specification with guidance at the organization level for quantification and reporting of greenhouse gas emissions and removals
ISO14064-2: Specification with guidance at the project level for quantification, monitoring and reporting of greenhouse gas emission reductions or removal enhancements
ISO14064-3: Specification with guidance for the verification and validation of greenhouse gas statements

5. Carbon Credit Price Index

While Hong Kong is still exploring the feasibility to have a platform for carbon trading exchange, the Company has made references to other international exchange platform or publicly available sources for the current market prices:

As of Country/Region Product(Quote) Individual exchange/ publicly available sources for reference:
27/1/2021 China CEA(RMB56.00 per tonne) Exchange: Shanghai Environmental and Energy Exchange https://www.cneeex.com/c/2022-01-27/491999.shtml

27/1/2022 Europe EUA Futures - Jan 22(EUR89.00 per contract) Exchange: Intercontinental Exchange https://www.theice.com/products/197/EUA-Futures/data?marketId=6817108

27/1/2022 California, US CBL California Carbon Allowance Vintage-Specific 2021 Feb 22(USD29.59 per contract) Exchange: New York Mercantile Exchange
https://tinyurl.com/2p97hrrf

30/9/2021 Australia Australian Carbon Credit Units(AUD26.50 per certificate) Source: Clean Energy Regulator, Australian Government
https://tinyurl.com/bddbrmyv

6. Hong Kong's Climate Action Plan 2050

The Government today (October 8) announced Hong Kong's Climate Action Plan 2050, setting out the vision of "Zero-carbon Emissions.Liveable City.Sustainable Development", and outlining the strategies and targets for combating climate change and achieving carbon neutrality.
< https://www.info.gov.hk/gia/general/202110/08/P2021100800588.htm?fontSize=1 >

7. China's Carbon Dioxide Peaking 2030 and Carbon Neutrality 2060

The Communist Party of China Central Committee and the State Council on Oct 24 jointly released a document titled: Full Text: Working Guidance For Carbon Dioxide Peaking And Carbon Neutrality In Full And Faithful Implementation Of The New Development Philosophy ( www.gov.cn )
< https://tinyurl.com/yc59ycnb >


Copyright 2022 ACN Newswire. All rights reserved. www.acnnewswire.comSynergy Group Holdings International Limited, stock code 1539.HK ("Synergy Group" or "The Group")(1) has successfully acquired verification statements of Greenhouse Gas (GHG) emissions granted by CMA Testing and Certification Laboratories under CMA Industrial Development Foundation Limited (CMA Testing(2)).

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